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RESEARCH AND DEVELOPMENT

42 CANCER CONTROL 2021

Authors' Note

The preparation of this manuscript did not require an ethical board

approval because it did not contain human or animal trials.

Declaration of Conflicting Interests

The author(s) declared no potential conflicts of interest with respect

to the research, authorship, and/or publication of this article.

Funding

The author(s) received no financial support for the research,

authorship, and/or publication of this article.

ORCID iD

Simone Badal https://orcid.org/0000-0001-5214-3896

Dr Simone Badal is a senior lecturer at The University of

the West Indies, Mona campus with extensive experience in

biochemistry, cellular biology and pharmacognosy. Her focus over

the years has been the identification of drug leads with anticancer

and chemopreventive potential using cell lines and microsomes

respectively. Her current focus is developing novel Black cancer

cell lines from the Caribbean, to contribute to a levelled anticancer

research playing field for Blacks with cancer.

based chemotherapy drugs (19) which contributes to poorer

patient survivability. Irrespective of the burden lung cancer

presents and the noteworthy disparity that exists, there is no

representation for Blacks among the cell line panels on ATCC

for lung cancer. Furthermore, of the 64 lung cancer cell lines

available, representation for Blacks is roughly 14% and for

Whites, roughly 80%.

Research with a focus on primary cancers of concern for

Blacks is lacking and cell lines when applied appropriately will

guide the development of drug leads with a targeted approach.

Organizations like, African Caribbean Cancer Consortium,

(AC3 https://ac3online.org), Prostate Cancer Transatlantic

Consortium (CaPTC) and Human Hereditary and Health in

Africa (H3A https://h3africa.org/) are engaged in research

efforts to understand cancers specific among the Black

population in Africa, the Caribbean and America. It is believed

that these research initiatives at the genome, transcriptome

and proteome levels taking lifestyle factors into account will

contribute to advancing more effective anticancer therapies

for Black men and women with cancer. However, needs to

be increased representation in cell line panels and among

cell lines in general from major suppliers such as ATCC and

ECACC, to better understand cancers of concern for Blacks.

Towards this end, our lab (AntiCancer Research Jamaica, www.

acrj.org.jm) has developed a methodology used to develop the

first cell line, ACRJ-PC28 (a prostate cancer cell line) from

the Caribbean, a region with high Black representation. We

believe this methodology will expand the representation of all

cancers of concern for Blacks. Concomitantly, there needs to

be a concerted effort among funding agencies, journal editors

and policymakers to steer the direction of research towards a

more inclusive approach. n

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