3
CONTENTS
Definition of terms 5
CHAPTER 1: The lay member"s role 7
Defining a lay member
Benefits of lay participation
Lay involvement in other similar contexts
Becoming a lay member
Consensus, compromise and disagreement
CHAPTER 2: Finding out about the ERB 11
Level and scope of ethical review by the ERB
The ERB"s aims and tasks
Participants in the ERB
Authority of the ERB
For institutional ERBs
The wider context in which the ERB operates
Communication and evaluation of the ERB
CHAPTER 3: The Three Rs 16
What lay members should expect
Approaches to each "R": Replacement
Reduction
Refinement
Advancing the 3Rs in practice
Sources of further information
CHAPTER 4: Reviewing project applications 25
The ERB"s role in project review
What lay members should expect
Key steps in project review:
1. Gathering information
2. Questions and discussions
Assessing benefits
Assessing harms to animals
3. Drawing conclusions
More general questions underlying harm-benefit