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GLOBAL CANCER POLICY-MAKING

Kampala (University of Makerere), Uganda, he joined the Melissa Adde has served as the Director of the Clinical Trials

National Cancer Institute (NCI), Bethesda, Maryland (1974), Office for the International Network for Cancer Treatment and

and became Chief of the Lymphoma Biology Section of the Research (INCTR) since 2000. In this capacity, she has

Pediatric Oncology Branch. coordinated multi-institutional clinical research studies in a

During the last 35 years he has had a particular interest in variety of malignancies, including ALL, Burkitt lymphoma,

cancer control in developing countries and has been involved in breast cancer, cervical cancer and retinoblastoma. These

the conduct of cancer control projects, clinical trials and basic studies have been conducted in many countries in Latin

research in many parts of the world, including India, Pakistan, America, Africa, and Asia. Her special skills include protocol and

Nepal, China, Mexico, Argentina, Brazil, Turkey, Tanzania, case report form design, data management, including teaching

Kenya, Nigeria and Egypt. In 2000, he became President of the basic skills required for conducting clinical research according to

International Network for Cancer Treatment and Research the principles of Good Clinical Practice, database design and

(INCTR) in Brussels and is now retired from NCI. Under his data analysis. She also monitored and continues to monitor the

leadership, INCTR has become an NGO in official relations with study presently on-going in African BL. She has made major

the World Health Organization (WHO), a Partner in the IAEA’s contributions to several publications related to work, conducted

Program of Action against Cancer and developed a bilateral in both the USA and in low- and middle-income countries about

alliance with Union for International Cancer Control (UICC). the treatment of NHLs and ALL.

Dr Magrath has authored over 360 original articles, She achieved her Bachelors’ of Science degree from the

chapters, reviews, commentaries and editorials relating University of Viriginia and her Masters’ of Science degree from

primarily to the pathogenesis and treatment of malignant the Catholic University of America, both in nursing. Ms Adde

lymphomas, pediatric cancers, cancer in developing countries joined the National Institutes of Health (NIH), USA in 1978 and

and EBV. He has also edited several books, including worked as a clinical nurse in the Pediatric Oncology Branch. She

Pathogenesis of Leukemias and Lymphomas; New served in both the inpatient wards and outpatient clinic and

Directions in Cancer Treatment; The Non-Hodgkin's developed a special interest in childhood acute lymphoblastic

Lymphomas; and Gene Therapy. His latest volume The leukemia (ALL) and non-Hodgkin’s lymphomas (NHL). She later

Lymphoid Neoplasms was published in 2010. joined the National Cancer Institute (NCI) of NIH where she

Dr Magrath has served on the board of a number of cancer worked as a Research Nurse Specialist for the Pediatric

journals and numerous committees. Most recently he served as Oncology Branch’s Lymphoma Biology Section. She coordinated

a member of the WHO Technical Committee on Cancer Control national studies in the treatment of Burkitt lymphoma (BL) and

and the Steering Committee for the Control of Cervical Cancer. other NHLs in children, adolescents and adults. In addition, she

He has also won a number of awards, including the Khanolkar coordinated multi-institutional studies of the treatment of ALL

Award, the Cairo University Shield, the Bhoruka Award (India), in India and Egypt.

and an recognition award from the Arab American Cancer

Foundation.

References

1. 5.

Ngoma, T., Adde, M., Durosinmi, M., Githag’a, J., Aken’Ova, Y., Kaijage, J., Adeodou, O., Naresh, K.N., Ibrahim, H.A., Lazzi, S., Rince, P., Onatari, M., Ambrosio, M.R., Bilhou-

Rajab, J., Brown, B.J., Leoncini, L., Naresh, K., Raphael, M., Hurwitz, N., Scanlan, P., Nabera, C., Amen, F., Reid, A., Mawanda, M., Calbi, V., Ogwang, M., Rogena, E.,

Rohatiner, A., Venzon, D., Magrath, I. Treatment of Burkitt lymphoma in equatorial Byakika, B., Sayed, S., Moshi, E., Mwakigonja, A., Raphael, M., Magrath, I., Leoncini, L.

Africa using a simple three-drug combination followed by a salvage regimen for Diagnosis of Burkitt lymphoma using an algorithmic approach – applicable in both

patients with persistent or recurrent disease. Br J Haematol 2012 Sep; 158(6), 749- resource-poor and resource-rich countries. Br J Haematol 2011 154: 770-776.

62. Doi:10.111/j.1365-2141.2012.09236x Epub 2012 Jul 30. 6.

WHO classification of tumours of the haemopoietic and lymphoid tissues (4th ed).

2.

Magrath, I.T. African Burkitt’s lymphoma. History, biology, clinical features, and Eds Swerdlow, S.H., Campo, E., Harris, N.L., Jaffe, E.S., Pileri, S.A., Stein, H., Thiele, J.,

treatment. Am J Pediatr Hematol Oncol 1991 Summer; 13(2): 222-246. Review. Vardeman, J. W. 2008, WHO, IARC, Lyon, France.

3. 7.

Magrath, I. Towards curative therapy in Burkitt lymphoma: the role of early African Twahirwa, A. Sharing the burden of sickness: mutual health insurance in Rwanda.

studies in demonstrating the value of combination therapy and CNS prophylaxis. Adv Bulletin of the World Health Organization 2008 86(11); 823-824.

Hematol 2012 Article ID 13608. Doi: 10.1155/2012/130680. http://who.int.bulletin/volumes/86/11/08-021108/en.index.html.

4. 8.

Naresh, K.N., Raphael, M., Ayers, L., Hurwitz, N., Calbi, V., Rogena, E., Sayed, S., Rosenberg, T. In Rwanda, health care coverage that eludes the U.S. Opinionator, New

Sherman, O., Ibrahim, H.A., Lazzi, S., Mourmouras, V., Rince, P., Githang’a, J., Byakika, York Times 2012 Jul 3.

B., Moshi, E., Durosinmi, M., Olasadoe, B.J., Oluwasola, O.A., Akang, E.E., Aken’Ova, Y., 9.

Msolla, P. Issues of higher education in Tanzania.

Adde, M., Magrath, I., Leoncini, L. Lymphomas in sub-Saharan Africa – what can we http://siteresources.worldbank.org/INTWBISFP/Resources/0_Prof_Msolla.pdf

learn and how can we help in improving diagnosis, managing patients and fostering

translational research? Br J Haematol 2011 Jun; 154: 696-703.

CANCER CONTROL 2013 33

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